| Date | Topic & Exercise | Readings |
| Aug 25 |
Introduction | - |
| Sept 1 |
Probability & Statistics | Inv. 1 |
| Sept 8 |
Drosophila familiarization Set up two experiments with the "Lobed" gene: - A comparison of variation in expressivity due to genetics and environment ("expressivity") - Incomplete penetrance in a monohybrid cross ("penetrance") |
Inv. 3 Inv. 4 |
| Sept 15 |
Independent assortment and gene interaction in maize Set up selection & drift experiments ("S&D") Clear penetrance & expressivity experiments |
Inv. 2 Inv. 5 |
| Sept 22 |
Analysis of variable expressivity Set up trihybrid cross for gene mapping experiment ("THC") Clear S&D experiments |
Inv. 6 Inv. 4 |
| Sept 29 |
Count & transfer F1 from S&D experiments Clear penetrance experiment Clear parentals from THC |
Inv. 5 |
| Oct 6 |
Analysis of incomplete penetrance in a monohybrid cross Make THC test cross Clear S&D experiments |
Inv. 4 |
| Oct 13 | Fall Break F1 cleared from THC |
|
| Oct 20 |
Lab Quiz Count & transfer F2 from S&D experiments |
Inv. 5 |
| Oct 27 |
Linkage analysis Clear S&D experiments |
Inv. 6 |
| Nov 3 |
Human karyotype analysis Count & transfer F3 from S&D experiments |
Inv. 7 Inv. 5 |
| Nov 10 |
Chromatography of eye pigments Clear S&D experiments |
Inv. 8 |
| Nov 17 |
Protein electrophoresis | Inv. 9 |
| Nov 24 |
Count F4 and terminate S&D experiments Selection and genetic drift |
Inv. 5 |
| Dec 1 |
Lab Quiz |
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